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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
NUP107
All Species:
31.52
Human Site:
T499
Identified Species:
57.78
UniProt:
P57740
Number Species:
12
Phosphosite Substitution
Charge Score:
0
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P57740
NP_065134.1
925
106374
T499
V
F
E
E
L
Q
A
T
D
K
K
R
V
L
E
Chimpanzee
Pan troglodytes
XP_522462
925
106407
T499
V
F
E
E
L
Q
A
T
D
K
K
R
V
L
E
Rhesus Macaque
Macaca mulatta
XP_001117201
925
106577
T499
V
F
E
E
L
Q
A
T
D
K
K
R
V
L
E
Dog
Lupus familis
XP_531670
686
80198
R315
S
L
V
E
Q
E
I
R
T
S
V
V
N
L
D
Cat
Felis silvestris
Mouse
Mus musculus
Q8BH74
926
106699
T500
V
F
E
E
L
Q
A
T
D
K
K
R
V
L
E
Rat
Rattus norvegicus
P52590
926
107190
T500
V
F
E
E
L
Q
A
T
D
K
K
R
V
L
E
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511475
975
112083
T549
V
F
E
E
L
Q
A
T
D
K
K
R
V
L
E
Chicken
Gallus gallus
XP_416082
885
102049
L483
V
I
Q
K
F
I
I
L
G
D
V
D
G
L
M
Frog
Xenopus laevis
NP_001091312
916
105253
T490
V
F
E
E
L
Q
A
T
D
K
K
R
V
L
E
Zebra Danio
Brachydanio rerio
NP_001025338
919
105378
T494
V
F
E
E
I
Q
A
T
E
S
K
R
V
L
D
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_609446
845
97363
Q474
H
I
V
L
F
L
R
Q
I
G
R
V
E
Q
E
Honey Bee
Apis mellifera
XP_397116
878
102262
D488
K
E
L
H
A
S
K
D
P
K
I
R
M
E
S
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
XP_791160
1004
115439
H573
I
F
Q
E
L
H
A
H
P
N
Q
K
V
E
A
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
98.9
98.4
70.8
N.A.
91.2
91.5
N.A.
82.8
78.1
74.8
67.3
N.A.
32
33.1
N.A.
43.9
Protein Similarity:
100
99.3
99.3
72.2
N.A.
95.5
95
N.A.
89
86.5
86.3
81.8
N.A.
50.8
53.7
N.A.
61.9
P-Site Identity:
100
100
100
13.3
N.A.
100
100
N.A.
100
13.3
100
73.3
N.A.
6.6
13.3
N.A.
33.3
P-Site Similarity:
100
100
100
26.6
N.A.
100
100
N.A.
100
26.6
100
93.3
N.A.
13.3
20
N.A.
60
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
0
0
8
0
70
0
0
0
0
0
0
0
8
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
0
0
0
0
0
8
54
8
0
8
0
0
16
% D
% Glu:
0
8
62
77
0
8
0
0
8
0
0
0
8
16
62
% E
% Phe:
0
70
0
0
16
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
0
0
0
0
0
0
8
8
0
0
8
0
0
% G
% His:
8
0
0
8
0
8
0
8
0
0
0
0
0
0
0
% H
% Ile:
8
16
0
0
8
8
16
0
8
0
8
0
0
0
0
% I
% Lys:
8
0
0
8
0
0
8
0
0
62
62
8
0
0
0
% K
% Leu:
0
8
8
8
62
8
0
8
0
0
0
0
0
77
0
% L
% Met:
0
0
0
0
0
0
0
0
0
0
0
0
8
0
8
% M
% Asn:
0
0
0
0
0
0
0
0
0
8
0
0
8
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
16
0
0
0
0
0
0
% P
% Gln:
0
0
16
0
8
62
0
8
0
0
8
0
0
8
0
% Q
% Arg:
0
0
0
0
0
0
8
8
0
0
8
70
0
0
0
% R
% Ser:
8
0
0
0
0
8
0
0
0
16
0
0
0
0
8
% S
% Thr:
0
0
0
0
0
0
0
62
8
0
0
0
0
0
0
% T
% Val:
70
0
16
0
0
0
0
0
0
0
16
16
70
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _